Triple Helix: Designing a New Molecule of Life
By SCIENTIFIC AMERICAN
Added: Mon, 24 Nov 2008 00:00:00 UTC
Thanks to SPS for the link.
For all the magnificent diversity of life on this planet, ranging from tiny bacteria to majestic blue whales, from sunshine-harv est ing plants to mineral-digesting endoliths miles underground, only one kind of âlife as we know itâ exists. All these organisms are based on nucleic acids—DNA and RNA—and proteins, working together more or less as described by the so-called central dogma of molecular biology: DNA stores information that is transcribed into RNA, which then serves as a template for producing a protein. The proteins, in turn, serve as important structural elements in tissues and, as enzymes, are the cellâs workhorses.
Yet scientists dream of synthesizing life that is utterly alien to this world—both to better understand the minimum components required for life (as part of the quest to uncover the essence of life and how life originated on earth) and, frankly, to see if they can do it. That is, they hope to put together a novel combination of molecules that can self-organize, metabolize (make use of an energy source), grow, reproduce and evolve.
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