Polar Bear Origins Traced to a Single Bear
By MARK BROWN - WIRED
Added: Fri, 08 Jul 2011 03:35:54 UTC
All living polar bears can trace their genetic lineage back to a single, female ancestor — a brown bear from Ireland, who lived around 20,000 to 50,000 years ago.
Thanks to climate change in the North Atlantic ice sheets around the time of the last ice age, the two types of bears would have periodically overlapped. In Ireland, it appears that they interbred, leading to a hybridisation event that plopped maternal DNA from brown bears into polar bears.
This event probably led to a fixation of the modern polar bear’s mitochondrial DNA, where a drastic reduction in genetic variation meant the entire gene pool was flooded with just one form of a particular gene, from just one female bear.
Researchers can figure this out thanks to that oh-so helpful mitochondrial DNA (mtDNA). This is a maternal part of the genome that is — unlike most of the nuclear DNA — passed down exclusively from the mother to her offspring. The sperm’s tiny cache of mtDNA, on the other hand, is destroyed upon fertilisation.
This allows us to connect the maternal lines and trace back a species’ genetic lineage through the mother’s line. We’ve done it with humans too, and found that all living humans descend from one woman in Africa — we call her Mitochondrial Eve.
Previous researchers have suggested that the polar bear’s “eve” lived on the ABC Islands — the Alaskan islands of Admiralty, Baranof, and Chichagof — only 14,000 years ago. But a new international team, lead by Beth Shapiro from Penn State University, has found a much earlier inter-breeding event that led to brown bear mtDNA creeping into the polar bear gene pool.
“We used DNA from living polar bears, and DNA from fossils around the world,” Mark Thomas, from University College London’s research department of genetics, evolution and environment and co-author of the paper, told Wired.co.uk in a phone interview.
In all, 242 brown bear and polar bear mitochondrial lineages throughout the last 120,000 years and across multiple geographic range were sampled. They found that the fixation of the mitochondrial genome likely occurred during or just before the peak of the last ice age, possibly as early as 50,000 years ago, and near present-day Ireland.
Those Irish brown bears are, of course, now extinct. They died out roughly 9,000 years ago.
- - PhysOrg.com Comments
Using a process called paleo-experimental evolution, Georgia Tech researchers have resurrected a 500-million-year-old gene from bacteria and inserted it into modern-day Escherichia coli (E. coli) bacteria. This bacterium has now been growing for more than 1,000 generations, giving the scientists a front row seat to observe evolution in action. Credit: Georgia Institute of Technology
- - Sense About Science 6 Comments
Welcome to this questions and answer session on cross fertilisation, which has also been called contamination, with Wendy harwood and Huw Jones.
Rothamsted Research - YouTube/Sense... 79 Comments
Add your support to the appeal from scientists at the publicly funded Rothamsted Research: Don't Destroy Our Research.
Edyta Zielinska - TheScientist 7 Comments
Genes shared across species that produce different phenotypes—deafness in humans and directional growth in plants—may reveal new models of disease.