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← How to Make Eyeball Stew - Editor’s choice in developmental biology

How to Make Eyeball Stew - Editor’s choice in developmental biology - Comments

rod-the-farmer's Avatar Comment 1 by rod-the-farmer

Reducible complexity

Thu, 15 Mar 2012 00:02:02 UTC | #927171

Dwegner's Avatar Comment 2 by Dwegner

god did it!

Thu, 15 Mar 2012 03:24:39 UTC | #927285

Alan4discussion's Avatar Comment 3 by Alan4discussion

Regeneration of some organs for transplants into patients, is already possible, -

http://ngm.nationalgeographic.com/2011/03/big-idea/organ-regeneration-text

The synthetic scaffold of an ear sits bathed in cartilage-producing cells, part of an effort to grow new ears for wounded soldiers.

More than 100,000 people are waiting for organ transplants in the U.S. alone; every day 18 of them die. Not only are healthy organs in short supply, but donor and patient also have to be closely matched, or the patient's immune system may reject the transplant. A new kind of solution is incubating in medical labs: "bioartificial" organs grown from the patient's own cells. Thirty people have received lab-grown bladders already, and other engineered organs are in the pipeline.

While this is in its early stages, the ability to grow new eyes would be a welcome addition.

Thu, 15 Mar 2012 10:54:11 UTC | #927408

SaganTheCat's Avatar Comment 4 by SaganTheCat

Comment 1 by rod-the-farmer :

Reducible complexity

quite. in biology; what use is a half arsed argument?

Thu, 15 Mar 2012 11:58:06 UTC | #927435

drumdaddy's Avatar Comment 5 by drumdaddy

Hats off to Dr. Sasai for his amazing progress. After these experimental cells die I hope that he is shipping them off to Rick Santorum for proper burial or Mitt Romney for postmortem baptism.

Thu, 15 Mar 2012 13:23:55 UTC | #927460

Alan4discussion's Avatar Comment 6 by Alan4discussion

Comment 5 by drumdaddy

After these experimental cells die I hope that he is shipping them off to Rick Santorum for proper burial or Mitt Romney for postmortem baptism.

You realise that while cats and dogs are not allowed in, RC heaven is over-run with the souls of human zygotes which failed to implant after about 4 days -( probably far outnumbering any human "souls")!!!!! Like so many who come to this site to argue their nonsense, they don't know the difference between human tissue (such as an amputated leg) and human beings (which have a brain - some allegedly - although it could be argued their brains are "as new" - never having been used! - undeveloped is probably more accurate).

Thu, 15 Mar 2012 14:08:48 UTC | #927474

ShadowMind's Avatar Comment 7 by ShadowMind

I'm waiting (hoping) for some-one to figure out how to use stem cells to grow a new eye lens (ready for implanting). That will be one of the most difficult challenges, but most useful results, in stem cell experimentation (IMHO). But this self-assembly trick is very impressive.

Fri, 16 Mar 2012 01:09:33 UTC | #927673

DavidMcC's Avatar Comment 8 by DavidMcC

NIH paper

The Eye Organizes Neural Crest Cell Migration

Abstract

In the anterior vertebrate head, a population of neural crest cells (NCCs) migrates to the periocular mesenchyme and makes critical contributions to the developing eye and orbit. Early in vertebrate development, the emerging eye is surrounded by mesenchymal cells derived from both lateral plate mesoderm and neural crest (NC), which together form the periocular mesenchyme (POM). In the anterior segment of the eye, POM cells give rise to the corneal endothelium, keratocytes of the corneal stroma, the ciliary muscle, iris stroma, the sclera, choroidal pericytes, and the trabecular meshwork. In the periphery of the eye, these cells form orbital cartilages and bones, blood vessels, as well as connective tissue associated with the extraocular muscles.

In other words, he might get a lot closer to an actual eye (apart from the lens - sorry, ShadowMind!) if he just stirred in some mesenchymal stem cells to go with the retinal progenitor cells that he appears to have created (which apparently went on to differentiate into layers of the retina, but in the absence of mesenchymal stem cells). It would almost certainly still not be a complete eye, though, as it might well still lack an optic nerve as well as a lens.

Fri, 16 Mar 2012 14:09:14 UTC | #927805

Anonymous's Avatar Comment 9 by Anonymous

Comment Removed by Moderator

Mon, 19 Mar 2012 03:29:04 UTC | #928535

Celeste's Avatar Comment 10 by Celeste

Practical application for evolution and we will prove the crazy Creationists are wrong, once and for all -- Let's just take all the parts of the eye, shake them up, and watch them self assemble. Poof. "Nothing" did it again!

Sat, 25 May 2013 17:06:25 UTC | #951391

JHJEFFERY's Avatar Comment 11 by JHJEFFERY

Excellent!!

Written by someone who has no earthly idea about evolution. Therefore the sky fairy did it.

Thu, 20 Jun 2013 23:16:06 UTC | #951394